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Search resuls for: "Foghorn"


8 mentions found


☆ Most N.Y.C. Drivers Who Honk Are Breaking the Law. Can They Be Stopped?
  + stars: | 2024-04-13 | by ( Erin Nolan | ) www.nytimes.com   time to read: +1 min
About a minute later, a deep, foghorn-like honk rumbled from a dump truck as it turned onto 89th Street. Speaking loudly over the horns of impatient drivers, several locals said in interviews that they were unbothered by the constant honking. “It just feels like the soundtrack to the city.”Using a vehicle horn when there is no “imminent danger” is prohibited under New York City’s noise code. A small number of local officials, noise experts and activists have pushed the city for decades to enforce the law. But catching offenders in the act is difficult, and in a city notorious for its aggressive driving culture and heavy traffic, squashing the urge to honk is an uphill battle.
Persons: toots, “, ”, Erin Clement Organizations: Columbus Locations: Manhattan, New York
☆ Flipping a Switch and Making Cancers Self-Destruct
  + stars: | 2023-07-26 | by ( Gina Kolata | More About Gina Kolata | ) www.nytimes.com   time to read: +1 min
Within every cancer are molecules that spur deadly, uncontrollable growth. What if scientists could hook those molecules to others that make cells self-destruct? Could the very drivers of a cancer’s survival instead activate the program for its destruction? “It’s very cool,” said Jason Gestwicki, professor of pharmaceutical chemistry at the University of California, San Francisco. “It turns something the cancer cell needs to stay alive into something that kills it, like changing your vitamin into a poison.”
Persons: Gerald Crabtree, ”, Crabtree, Nathanael S, Gray, “, Jason Gestwicki Organizations: Stanford, redwoods, Foghorn Therapeutics, University of California Locations: Santa Cruz, San Francisco
☆ Pfizer, Flagship Pioneering to invest $100 mln in drug discovery
  + stars: | 2023-07-18 | by ( ) www.reuters.com   time to read: +2 min
July 18 (Reuters) - U.S. drugmaker Pfizer (PFE.N) and venture firm Flagship Pioneering on Tuesday said they would invest $100 million together to develop up to 10 new potential drugs for areas including internal medicine, oncology, infectious diseases and immunology. Flagship, which has incubated biotech companies, most famously Moderna Inc (MRNA.O), and Pfizer will each invest $50 million. Flagship's drug discovery initiative Pioneering Medicines will lead the exploration process. Paul Biondi, president of Flagship's Pioneering unit and a former top Bristol Myers Squibb (BMY.N) executive, said the partnership will take advantage of Flagship's abilities to develop novel technologies towards bigger disease areas. Drug developers such as Denali Therapeutics (DNLI.O), Foghorn Therapeutics (FHTX.O) and Sana Biotechnology (SANA.O) are some of the other companies backed by Flagship.
Persons: Paul Biondi, Biondi, Mikael Dolsten, Foghorn, Bhanvi, Michael Erman, Shilpi Majumdar, Alexandra Hudson Organizations: drugmaker Pfizer, Moderna Inc, Pfizer, Flagship's, Bristol Myers Squibb, Flagship, Therapeutics, Foghorn Therapeutics, Sana Biotechnology, Alexandra Hudson Our, Thomson Locations: Bengaluru, New Jersey
☆ A Norwegian guy woke Russian diplomats in Oslo after 2 a.m. with an air raid siren on the anniversary of the invasion of Ukraine
  + stars: | 2023-02-27 | by ( Mia Jankowicz | ) www.businessinsider.com   time to read: +3 min
A 73-year-old Norwegian man woke Russian diplomats with an 'air raid siren' late on Friday. His noisy protest in Oslo came on the anniversary of Russia's invasion of Ukraine. He wanted Russians to wake up to the war, he told Norwegian outlet Nettavisen. On Friday night at around 2.30 a.m. local time, Kjetil Krane carried a loudspeaker out to an apartment block known to house workers at Oslo's Russian embassy, Nettavisen reported. In a video shared by Nettavisen, Krane can be seen wearing a T-shirt that says "wake a Russian" in Norwegian as a newly-awoken resident peers out of a window.
☆ Opinion | We Can’t Just Give Up and Shrug in Silence
  + stars: | 2023-01-30 | by ( Gail Collins | Bret Stephens | ) www.nytimes.com   time to read: +2 min
No matter how much Kevin McCarthy swears that won’t involve cuts to Social Security or Medicare, it’s almost impossible to imagine they aren’t on the table. If Congress cuts spending to balance the budget as some Republicans have suggested, it could mean big cuts to very popular programs like Social Security and Medicare. Bret: Other than trying to find ways to slow the rate of spending growth, I can’t imagine there would be cuts to either program. They’re popular with Republican voters, too, after all. For some reason, Social Security payroll taxation stops at about $160,000.
☆ A 33-year market vet shares why history shows stocks will likely fall more than 20% further before bottoming as a recession barrels toward the US economy
  + stars: | 2023-01-07 | by ( William Edwards | ) www.businessinsider.com   time to read: +5 min
But Lebowitz thinks there's a much greater chance that a recession occurs, forcing the Fed to back off. And then there's the inverted yield curve, which has preceded every recession since the 1960s. RIA AdvisorsIt's also not a good environment for stocks because yield curve inversions have usually meant large downward earnings revisions, which haven't happened yet. RIA AdvisorsAnother look at history, Lebowitz said, shows that a recession has to be already underway before stocks can bottom out. The yield curve, Chicago PMI, and other analyses argue it's a matter of when but if a recession occurs.
☆ Wanted: Two lighthouse keepers for tiny island in San Francisco Bay. Must have 'high-quality culinary experience' and a captain's license.
  + stars: | 2022-12-25 | by ( Ryan Hogg | ) www.businessinsider.com   time to read: +3 min
Two custodians for a historic lighthouse and hotel in San Francisco Bay are being recruited. The East Brother Light Station is looking for two people to become lighthouse keepers for two years on the tiny island just off Point San Pablo in Richmond. Former innkeepers Tiffany Danse (left) and Tyler Waterson (right). Run boat service to the mainland. Run boat service to the mainland again," the Chronicle wrote.
☆ ‘Glass Onion’ sharpens the ‘Knives Out’ formula in a polished Netflix sequel
  + stars: | 2022-11-23 | by ( Review Brian Lowry | ) edition.cnn.com   time to read: +3 min
CNN —Rising to the challenge of matching its successful predecessor, “Glass Onion: A Knives Out Mystery” maintains the razor-sharp formula, with a setup that feels even more conspicuously like an Agatha Christie homage before an extremely clever series of twists kick in. Writer-director Rian Johnson again assembles a solid cast behind Daniel Craig, but it’s his use of language – where nary a word is wasted – that finally gives the sequel its edge. Netflix opportunistically stepped up to acquire the “Knives Out” franchise and, departing from its usual “Stroke the filmmakers’ egos” approach to theatrical distribution, will actually give the movie a wide one-week-only release before it hits the streaming service in late December. Happily, “Glass Onion” finds new layers to explore, in a way that makes the prospect of a new “Knives Out Mystery” every few years sound like a perfectly reasonable idea, wherever and however one chooses to consume it. “Glass Onion: A Knives Out Mystery” premieres November 23 in US theaters and December 23 on Netflix.
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